Photodynamic therapy (PDT) utilizing Photofrin is proving to be effective for the treatmentof early stage lung cancers. The effect of PDT utilizing YAG-OPO laser as newlight source was evaluated in 26 patients (29 lesions) with early stage lung cancers. YAG-OPOlaser is solid state tunable laser which is easy to change wavelength between 620 and670 nm exciting various kinds of photosensitizers. Moreover, YAG-OPO laser is more reliable,smaller and has less consumables than argon-dye laser or excimer-dye laser. Asthe result of PDT with YAG-OPO laser, complete remission (CR) was obtained in 82.6%of the 29 lesions, partial remission (PR) in 13.8% and no change (NC) was obtained in3.4%. We conclude that PDT utilizing YAG-OPO laser is efficacious in the treatmentof early stage lung cancers and can achieve complete remission.
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